Bacteria Classification via Surface Enhanced Raman Spectroscopy and Principal Component Analysis
نویسندگان
چکیده
Surface-enhanced Raman scattering (SERS) provides rapid fingerprinting of biomaterial in a non-destructive manner. The adsorption of colloidal silver to biological material suppresses native biofluorescence while increasing the normal Raman signal via the surfaceenhanced Raman effect. This work validates the applicability of qualitative SER spectroscopy, utilizing principal component analysis (PCA) to show discrimination of biological threat simulants, based upon multivariate statistical confidences limits bounding known data clusters. Several strains of Bacillus spores are investigated along with Pantoea agglomerans,and Brucella noetomae.
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تاریخ انتشار 2008